Woman standing pulling measuring tape around waist.Fat around the middle manufactures an array of chemical messengers including blood-clotting agents, substances that contract blood vessels and raise blood pressure, inflammatory agents, hormones and molecules that control hunger. 

Fat cells are also able to produce an immune response in the body, which causes inflammation.

Fat cells secrete oestrogen and two other compounds — tumour necrosis factor alpha and resistin — both of which interfere with the functioning of insulin.

Not all fat in the body behaves in the same way and it is the fat around the middle that is more metabolically active than fat elsewhere.

It has also been called “toxic fat” because it increases your risk of heart disease, high blood pressure, stroke, cancer and Type 2 diabetes.

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