Two hundred and forty four postmenopausal women were given 180 micrograms of vitamin K2 per day or a placebo for three years. Bone mineral density, bone mineral content, vertebral fracture risk, and measures of bone strength were taken at baseline and after one, two and three years of treatment.
- Women in the placebo group had the expected age-related decline in bone mineral density and bone mineral content.
- Compared with placebo, Vitamin K2 had a positive effect on bone health after three years.
- Vitamin K2 significantly decreased bone mineral content and bone mineral density losses in the lumbar spine and femoral neck.
- Vitamin K2 improved bone strength and decreased vertebral fracture risk.
Source: (Osteoporos Int 2013; DOI 10.1007/s00198-013-2325-6)